Ingredient Research Magnesium Glycinate & Citrate

Research comparing magnesium citrate and magnesium glycinate for hydration specifically is limited. However, existing studies provide insights into the bioavailability and hydration effects of these compounds that can help evaluate their potential.

Evidence:

1. Magnesium Citrate:

• Magnesium citrate is highly soluble in water and has demonstrated superior bioavailability compared to magnesium oxide, enhancing magnesium absorption and urinary magnesium levels (Lindberg et al., 1990).

• Studies suggest it improves systemic magnesium availability, which can enhance hydration through its osmotic properties (Afitska et al., 2021).

• Its effects on hydration are also supported in endurance contexts, where magnesium-enriched hydration mixes reduced muscle cramps and improved fluid balance (Kharait, 2022).

2. Magnesium Glycinate:

• Magnesium glycinate, being chelated with glycine, is well absorbed and less likely to cause gastrointestinal side effects than some other forms (Blaquiere & Berthon, 1987).

• However, evidence regarding its specific effects on hydration or osmotic balance is scarce. Its main advantage lies in its stability and tolerability rather than hydration efficacy.

• At higher doses of magnesium it would make sense to use Magnesium Glycinate. Unless the product in question is aiming to stimulate a laxative effect, which is usually seen at dosages of around 400mg Magnesium Citrate.

• Sleep Support: Magnesium glycinate is chelated with glycine, an amino acid that promotes relaxation and supports sleep by enhancing the production of calming neurotransmitters like GABA. This makes it an excellent choice for reducing stress and improving sleep quality (Blaquiere & Berthon, 1987).

Conclusion:

Magnesium citrate is likely the better option for enhancing hydration due to its higher solubility, bioavailability, and osmotic properties that support fluid retention and balance. 

Magnesium glycinate is the optimal choice for Full Moon due to its calming and sleep-enhancing properties, despite its lack of evidence for hydration benefits. Conversely, magnesium citrate in Wolf Hydrate effectively supports hydration without triggering laxative effects, thanks to its low dosage. This differentiation ensures each formula is precisely tailored to its intended purpose.